In silico systems for uncovering off-target liabilities
Prous Institute SYMMETRY is a powerful in silico solution for drug R&D. Its Global Mechanism of Action (GMoA) model facilitates the detection of off-target activities leading to adverse effects. GMoA is based on an expertly curated, updated training set that includes structures from patents in addition to public databases for comprehensive coverage of novel chemical space. In addition, we’ll present the new OFF-TARGET platform that alerts scientists of the latest target class liabilities.