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From Our Blog
Latest From The Blog
How to Inspect Surgical Scissors
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Protect the investment you have made in surgical instruments and improve the outcomes of your surgeries by regularly inspecting your surgical scissors. Regular inspections ensure that your surgical scissors are in optimal working condition, allowing you to promptly identify and address common issues like dullness, misalignment, or damage. Inspections also help mitigate risks associated with the use of defective or damaged surgical scissors and promotes surgical safety, reducing the likelihood of adverse outcomes. By addressing minor issues early on and following regular cleaning, sterilization, and storage protocols, you can extend the usable lifespan of your surgical instruments, reducing the need for frequent replacements and the associated costs...more
Join Us at MPS - June 10-14, Seattle
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Join WPI at Booth 14 at the MPS World Summit, June 10-13 in Seattle, WA. for a showcase of new research and the opportunity to network with colleagues and industry thought-leaders...more
Quality Control of Retinal Pigment Epithelial Cell Therapies
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Cell therapies have emerged as a promising approach for treating various medical conditions, offering the potential for regenerating damaged tissues, restoring normal cellular function, or even acting as cytotoxic cells that target and destroy diseased cells such as cancer cells. As the field of cell-based therapeutics and regenerative medicine continues to advance, ensuring the quality and safety of cell-based therapies is of paramount importance. Quality control measures play a critical role in the manufacturing process of cell therapies, with trans-epithelial electrical resistance (TEER) emerging as a valuable tool for assessing the integrity and functionality of cells used in these therapies. Here, we highlight the use of TEER for quality control of Retinal Pigment Epithelial (RPE) cells, a promising cell therapy for degenerative retinal diseases1...more
Enhancing Quality Control in Cell Therapies
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Cell therapies have revolutionized the field of regenerative medicine, offering promising treatments for a variety of medical conditions. Maintaining the safety, efficacy, and consistency of cell-based therapies is paramount for their successful application in clinical settings. Quality control measures play a vital role in evaluating the quality of these therapies, from development to administration. This article explores the current approaches to quality control in cell therapies, including the utilization of functional measurement techniques such as transepithelial electrical resistance (TEER), to ensure the quality and safety of these promising treatments...more
TEER in Ophthalmology for Advanced Research with RPE Cells
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Transepithelial electrical resistance (TEER) has emerged as a powerful tool in ophthalmology research and has become a standard method for study of retinal pigment epithelial (RPE) cell biology and the development of these cells as a therapeutic for retinal diseases such as Age-Related Macular Degeneration (AMD). The application of TEER in assessing the barrier function and integrity of RPE cell layers has significantly advanced our understanding of retinal diseases and paved the way for innovative therapeutic interventions including some of the most promising cell therapies to date. This article explores the use of TEER in ophthalmology research, with a focus on studies utilizing RPE cells for both research and clinical applications...more
Join Us at ARVO 2024 - Seattle, May 5-9!
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Join WPI May 5 - 9 in Seattle, Wash., for a showcase of new research and the opportunity to network with colleagues and industry thought-leaders...more
Electroporation vs Zebrafish Embryonic Transfection
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It has been found that transgenesis of vectors using Tol2 or other transposon-based systems promote stable expression. A standard pressure-based microinjection approach presents greater reliability, precision, and overall control when delivering material to embryos, often preferred over electroporation in zebrafish studies...more
PRESS RELEASE: WPI Partners with TotalLab to Introduce 21 CFR Part 11 into EVOM Product Line
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World Precision Instruments (WPI) is pleased to announce their strategic partnership with TotalLab, paving the way for the integration of 21 CFR Part 11 compliance into its esteemed EVOM family of products...more
VIDEO: How to Remove EVOM Auto Electrode Array Lock
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EVOM™ Auto, with both 24 and 96 HTS multiwell plate capability, is a high throughput screening (HTS) platform offering fast, noninvasive sample scanning by comparing electrical resistance measurements (transepithelial/transendothelial electrical resistance: TEER). TEER measurement experiments are simple to set up and less time consuming than more complex molecular studies. TEER measurement can be used as the primary scanning method to identify any physiological changes that can then be further evaluated by other methods. EVOM™ Auto can capture TEER measurements in 24 and 96 HTS multiwell plates from Corning, Millipore, or MatTek. The sample preparation time in these HTS plates is efficient, allowing for fast, multi-channel pipetting options.
The EVOM™ Auto autosampler ships with a red electrode array lock in place to prevent the electrode array connection port from moving during transit. Here you can see how to easily remove it without damaging the lock or the autosampler...more
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